It some cases one LSPI event will destroy an engine. For normal knock, the engine will pull timing to eliminate the knock when detected. The Ecoboost ECU is pretty good at pulling timing quickly to save the engine in these cases. Most tuners will also not tune your car to the ragged edge of what's safe. The risk for LSPI happening increase on a small displacement GDI turbo engine in low RPM, high-load situations when using certain motor oils.^This^ I mean, I'm not saying LSPI is made up, but if it was that huge of concern, wouldn't we be seeing all GDI engines grenading themselves prematurely? Or at least a good portion of them. In the video linked above, keep in mind who's giving the information. It's a sales guy. A really good sales guy at that. The southern accent really helps in sounding genuine. And being in sales myself, I can tell you the job of a sales guy is to make you believe you want (NEED) what I'm selling. With all research findings, you always have to look at who conducted the study and who is doling out the info. Like I said, I'm sure this is a real problem. But it seems this can be exacerbated by bad driving habits. You shouldn't be lugging the engine on ANY car. With 28k miles on my RS, running a tune for almost 18k of those, using Motorcraft 5W-50, I would think I would be seeing knock all over the place, which I don't. There are others that have mileage way beyond mine in the mileage thread. I mean, heck, @RedBaron80 just said he hit 109K a couple days ago. I would never imagine this engine holding out for that long. So I'm not going to lose any sleep over it, with my four 12-packs of Motorcraft 5W-50 I have in my garage (that I scored on a ridiculous deal posted on here a while ago). Shout out to @bbq_pork !!!
The causes for each LSPI event aren't super well understood but fortunately they are relatively infrequent, but when they do happen they're pretty catastrophic. Research has shown that certain oil additive packages and driving conditions (described above) will increase the chances of LSPI. Using an API SN+ oil will help reduce the chances of LSPI if you're super concerned, but I don't think you can get the Ford Motorcraft 5w-50 oil with the SN+ certification yet.